同济大学学报（医学版）2012，Vol.33Issue(5)：101-104,4.DOI:10.3969/j.issn1008-0392.2012.05.024
TCT联合血清SCC-Ag在宫颈病变筛查中的价值
TCT test and serum SCC-Ag in screening of cervical lesions
高月清 1翁雷 1孙静1
作者信息
- 1. 同济大学附属第一妇婴保健院妇科,上海 200040
- 折叠
摘要
Abstract
Objective To evaluate the application of thinprep cytology test (TCT) and the serum squamous cell carcinoms antigen (SCC-Ag) measurement in the cervical lesion screening. Methods TCT and serum SCC-Ag measurement were performed in 189 patients with cervical lesions. Based on the pathology diagnosis, specificity and sensitivity of these two screening methods were calculated. Results SCC-Ag had lower sensitivity and higher specificity than those of TCT (60. 32% vs 79. 36% and 92. 86% vs 70. 63% , P ＜ 0. 05). Co-test of these two methods increased the specificity to 96.31% , but decreased the sensitivity to 57. 14% with positive predictive value of 90. 00% and consistency rate to 83. 69%. There was significant difference between co-test and single TCT (P ＜ 0.05) . Conclusion In the cervical lesion screening, co-test of TCT and SCC-Ag decreased the false positive rate, increased the specificity and diagnosis coincidence rate. 关键词
TCT检测/SCC-Ag/宫颈病变/筛查Key words
thinprep cytology test/ squamous cell carcinom antigen/ cervical lesion/ screening分类
医药卫生引用本文复制引用
高月清,翁雷,孙静..TCT联合血清SCC-Ag在宫颈病变筛查中的价值[J].同济大学学报（医学版）,2012,33(5):101-104,4.
