世界中医药2012，Vol.7Issue(6)：493-495,3.
补脾祛风方对脾虚型特应性皮炎ECP及Th1/Th2细胞调节的影响
Regulation Effect of Bupi Qufeng Decoction on Serum ECP and Th1/Th2 Cell in Spleen Deficiency Type of Atopic Dermatitis Patients
摘要
Abstract
Objective:To study the regulation effect of Bupi Qufeng Decoction on ECP and Thl/Th2 cell in atopic dermatitis ( AD ) patients. Methods: A total of 101 cases of chosen medical records were randomly divided into treatment group and control group according to digital table. During the treatment, both groups were given compound Danggui Bohe paste for external use. Based on this, the treatment group was given Bupi Qufeng Decoction orally, while the control group was given loratadine orally. ECP、IFN -γand IL -4 count were determined before the treatment and four weeks after the treatment, and Thl and Th2 cells were detected by IFN - γ and IL -4. Re-sults:After the treatment, the level of ECP in the treatment group decreased significantly ( t = 18. 57,P < 0. 001 ), and the decrease range was greater than the control group ( t = 15. 22 , P < 0. 001 ); the level of Thl in treatment group significantly increased ( t = 3. 34 , P < 0. 01 ), and the increase range was greater than the control group( t = 2. 20,P < 0. 05 ); the level of Th2 in treatment group significantly reduced( t = 11. 87,P < 0. 001 ), and the reduction was greater than the control group( t = 1. 99, P < 0. 05 ); the value of Thl / Th2 in treatment group increased significantly ( t =4. 07,P <0. 001 ), and the increase range was more than the control group ( t =4. 64, P< 0.001 ). Conclusion: Treating spleen deficiency type of atopic dermatitis with Bupi Qufeng Decoction can effectively reduce serum ECP and adjust Thl / Th2 balance. Bupi Qufeng Decoction has better effect than loratadine.关键词
特应性皮炎/补脾祛风方/ECP/Th1/Th2Key words
Atopic dermatitis/Bupi Qufeng Decoction/ECP/Thl/Th2引用本文复制引用
郑永平,张玲,陈高飞,关健缨..补脾祛风方对脾虚型特应性皮炎ECP及Th1/Th2细胞调节的影响[J].世界中医药,2012,7(6):493-495,3.基金项目
中山市科技局2010年科技立项课题(编号:2010A056) （编号:2010A056）
