生命科学研究2012,Vol.16Issue(5):462-465,4.
伯氏疏螺旋体膜蛋白BmpA研究进展
Progresses on Borrelia burgdorferi Membrance Protein A (BmpA)
摘要
Abstract
Lyme disease, a global health concern, is a zoonosis, which has been a serious threat to human. The spiroehete Borrelia burgdorferi that is transmitted by the bite of hard tick (Ixodidae) is the pathogen of Lyme disease. Borrelia burgdorferi contains many membrane proteins with immungenicity and pathogenicity. Recent researches show that BmpA is an dominant immune protein of Borrelia burgdorferi, a laminin-binding protein, and an arthritogennic factor. Research progresses of BmpA protein in biological function, Lyme arthritis pathogenesis and diagnosis of lyme disease are reviewed.关键词
伯氏疏螺旋体/莱姆病/莱姆关节炎/伯氏疏螺旋体膜蛋白Key words
Borrelia burgdorferi/Lyme disease/Lyme arthritis/Borrelia burgdorferi membrance protein A (BmpA)分类
医药卫生引用本文复制引用
宝福凯,赖名耀,张云波,董坚,赵桂萍,陈明清,柳爱华..伯氏疏螺旋体膜蛋白BmpA研究进展[J].生命科学研究,2012,16(5):462-465,4.基金项目
国家自然科学基金资助项目(81060134) (81060134)
云南省自然科学基金资助项目(2007C069M) (2007C069M)