天然产物研究与开发2012，Vol.24Issue(9)：1292-1296,5.
响应面法优化超声辅助提取宣木瓜总皂苷提取工艺研究
Optimization of Ultrasound-assisted Extraction of Total Triterpenoid Saponins from Chaenomeles speciosa Using Response Surface Analysis
摘要
Abstract
Response surface methodology was used to optimize the ultrasound-assisted extraction of total triterpenoid saponins from Chaenomeles speciosa. The extraction efficiency of total triterpenoid saponins was investigated with respecting to four variables including time, temperature, ethanol concentration and liquid-to-solid ratio. On the basis of a series of one-factor-at-a-tirrje experiments, a polynomial regression model equation was fitted by the combined use of Box-Behnken experimental design and regression analysis. By analyzing the regression model using response surface analysis,the optimum extraction conditions of total triterpenoid saponins from C. speciosa were identified as follows ;61.69 min extraction time,62. 34 ^extraction temperature,70. 49% ethanol concentration and 1 = 30.57 g/mL solid-to-liquid ratio,and the extration efficiency of total triterpenoid saponins was up to 1. 55% under the optimized conditions. Confirmatory experiments indicated the good prediction ability of the established model.关键词
宣木瓜/总皂苷/超声/响应面Key words
Chaenomeles speciosa/total triterpenoid saponins/ultrasound {response surface analysis分类
医药卫生引用本文复制引用
潘国波,杨小明,丁艳,李媛媛,韩邦兴..响应面法优化超声辅助提取宣木瓜总皂苷提取工艺研究[J].天然产物研究与开发,2012,24(9):1292-1296,5.基金项目
江苏高校优势学科建设工程资助项目[苏政办发(2010)118号] （2010）
