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保留十二指肠胰头切除术与胰十二指肠切除术治疗慢性胰腺炎的比较研究

刘嘉哲 黄新余 王洪成 刘永志 郑起

外科理论与实践2012,Vol.17Issue(5):477-480,4.
外科理论与实践2012,Vol.17Issue(5):477-480,4.DOI:10.3969/j.issn.1007-1096.2012.05.018

保留十二指肠胰头切除术与胰十二指肠切除术治疗慢性胰腺炎的比较研究

Duodenum-preserving pancreatic head resection versus pancreaticoduodenectomy for chronic pancreatitis

刘嘉哲 1黄新余 1王洪成 1刘永志 1郑起1

作者信息

  • 1. 上海交通大学医学院附属第六人民医院普外科,上海200233
  • 折叠

摘要

Abstract

Objective To assess the safety and efficiency of duodenum-preserving pancreatic head resection (DPPHR) and pancreaticoduodenectomy (PD) in treatment of chronic pancreatitis. Methods Fifty-nine patients undergoing PD or DPPHR for chronic pancreatitis from Jan 2004 to Dec 2010 were retrospectively reviewed. The preoperative variables, operation data, mortality, morbidity and postoperative hospital stay after the two types of surgery were compared. Quality of life was assessed cross-sectionally using the standard Chinese version of the EORTC QLQ-C30 (version 3.0). Results Thirty-seven patients underwent PD and 22 underwent DPPHR for the treatment of chronic pancreatitis. The characteristics of patients were similar between the two groups. Estimated blood loss [(332±103) tnL vs (241±74) mL] , operation time[(310±91) min vs (249±71) min] and postoperative hospital stay [(14.3±9.0) days vs (9.4± 8.4) days] were all less for DPPHR patients (P<0.05). There was no postoperative death in either group. Morbidity (32.4% vs 31.8%, P>0.05) and quality of life scores did not differ between groups. Conclusions DPPHR is as effective as PD in relieving pain and improving quality of life in patients with chronic pancreatitis. Post-operative mortality and morbidity did not differ between two groups. DPPHR resulted in a shorter hospital stay, less blood loss and less operation time.

关键词

保留十二指肠胰头切除术/胰十二指肠切除术/慢性胰腺炎

Key words

Duodenum-preserving pancreatic head resection/ Pancreaticoduodenectomy/ Chronic pancreatitis

分类

医药卫生

引用本文复制引用

刘嘉哲,黄新余,王洪成,刘永志,郑起..保留十二指肠胰头切除术与胰十二指肠切除术治疗慢性胰腺炎的比较研究[J].外科理论与实践,2012,17(5):477-480,4.

外科理论与实践

OACSTPCD

1007-9610

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