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可疑AD患者和抑郁性假性痴呆患者大脑血流速度的比较

吕高萍 陈春莲 陆慧慧 蒋丽丽 王晶

西南国防医药2012,Vol.22Issue(9):932-934,3.
西南国防医药2012,Vol.22Issue(9):932-934,3.DOI:10.3969/j.issn.1004-0188.2012.09.002

可疑AD患者和抑郁性假性痴呆患者大脑血流速度的比较

Comparison of cerebral blood flow rate between patients suspected of alzheimer dementia and ones with depression pseudo - dementia

吕高萍 1陈春莲 2陆慧慧 2蒋丽丽 1王晶1

作者信息

  • 1. 541001广西桂林,桂林医学院附属医院神经内科
  • 2. 541001广西桂林,桂林医学院附属医院老年科
  • 折叠

摘要

Abstract

Objective To make comparison of differences in the cerebral blood flow rates between patients with suspected alzeheimer disease (AD) and the ones with depression pseudo - dementia. Methods Twenty patients with suspected AD and other 20 ones with depression pseudo - dementia in our hospital were selected. And 20 healthy volunteers were chosen as the controls. After receiving visual stimulation, their cerebral blood flow rates were detected by transcranial Doppler examination, and the differences were compared. Results The average blood flow rates of left and right side posterior cerebral artery, resting blood flow rates, blood flow rates at stimulation, and relative blood flow rates in the AD group and the pseudo - dementia group were all lower than those in the control group (P <0. 05). The blood flow rates at stimulation and relative blood flow rates of patients with AD were significantly lower than those of the patients with depression pseudo - dementia (P<0. 05). Conclusion Among the patients with suspected AD, the neurovascular coupled action is severely damaged, which can be used as the reference to distinguish AD from depression pseudo -dementia.

关键词

阿尔茨海默病/假性痴呆/大脑后动脉/血流速度

Key words

alzheimer disease/ pseudo - dementia/ posterior cerebral artery/ blood flow rate

分类

医药卫生

引用本文复制引用

吕高萍,陈春莲,陆慧慧,蒋丽丽,王晶..可疑AD患者和抑郁性假性痴呆患者大脑血流速度的比较[J].西南国防医药,2012,22(9):932-934,3.

基金项目

广西壮族自治区卫生厅计划课题资助项目(Z2011197) (Z2011197)

西南国防医药

OACSTPCD

1004-0188

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