西南国防医药2012，Vol.22Issue(10)：1086-1089,4.DOI:10.3969/j.issn.1004-0188.2012.10.018
心脏原发轻链型淀粉样变1例报告并文献复习
Report of cardiac primary light-chain amyloidosis in one case and literature review
郭华 1徐军 1缪东培 1包知达 1翟永平2
作者信息
- 1. 210002南京,南京军区南京总医院干部心内科
- 2. 210002南京,南京军区南京总医院血液病科
- 折叠
摘要
Abstract
Objective To discuss the clinical features, pathological characteristics, diagnosis, and treatment of cardiac primary light - chain amyloidosis. Methods A case of cardiac primary light - chain amyloidosis was reported, and relative literatures were reviewed. Results The main clinical features included heart failure, refractory hypotension, and low voltage and abnormal Q wave on the electrocardiogram, etc. The specificity of the ultrasonic cardiogram included the occurrence of particles in the cardiac muscle of endocardium and abnormal increase of monoclonal light chain. In the tissue biopsy, specific amyloidosis tissues could be observed after the staining by Congo red. The conventional treatment methods included MP or MD scheme ( melphalan plus prednisone or dexamethasone ). Conclusion Cardiac primary light - chain amyloidosis is rarely seen in clinic, and there are few specific clinical manifestations. Tissue biopsy and serum free light chain detection are the main methods for the final diagnosis, and MP and MD schemes are the treatment methods.关键词
淀粉样变性/心脏/病例报告Key words
amyloidosis/ heart/ case report分类
医药卫生引用本文复制引用
郭华,徐军,缪东培,包知达,翟永平..心脏原发轻链型淀粉样变1例报告并文献复习[J].西南国防医药,2012,22(10):1086-1089,4.
