摘要
Abstract
Objective To evaluate the relationship between the COPD assessment test ( CAT ), the lung function test, and the frequency of exacerbation in patients with chronic obstructive pulmonary disease ( COPD ). Methods Sixty-six COPD patients enrolled in the study. Lung volume and spirometry function were evaluated in stable COPD patients. The CAT score were collected and the Pearson s correlation coefficients were calculated. All the patients were followed up for 1 year, and the frequency and baseline of the exacerbation and the hospitalized exacerbation were recorded. Results The CAT score were 5 ~37( 17. 3 ± 5. 2 ) during the stable stage. In the lung function test, FEV, pred% was ( 52 ± 14 )% , and the IC pred% was ( 72 ± 21 )% . Negitive correlation was proved between the IC pred% and the CAT score ( r = - 0. 563 , P < 0.01), while no correlation of the indexes of FEV, pred% and FEV,/TV ( r = 0. 128, P > 0.05; r = 0. 145, P > 0. 05 ). In 48 exacerbations, 12 of them were hospitalized. The CAT scores were ( 23. 6 ± 8. 3 ) and ( 26. 8 ±4. 2 ) on the day of exacerbation, which is significantly higher than that of in the stable stage. The baseline CAT score were ( 16. 2 ±4. 6 ),( 17. 0 ± 3. 8 ),( 20. 1 ±6. 4 ),( 28.5 ± 12. 0 ) and ( 21.0 ±3. 2 ) separately in the patients who had no exacerbation, 1 time exacerbation, 2 times exacerbations, 3 times exacerbations and 4 times exacerbations. The baseline CAT score were higher in frequent exacerbators ( 21. 9 ±7.4 ) than unfrequent exacerbators ( 16. 5 ±4. 3 ),there was significant differences( P <0. 05 ). Conclusion The CAT score correlated with the lung function test results and was easily to be applied. The CAT score may be a good predictor in the COPD exacerbation.
关键词
肺疾病,阻塞性,慢性/COPD评估测试,肺功能/急性加重Key words
Pulmonary disease, obstructive, chronic/ COPD assessment test/ Respiratory function tests, Acute exacerbation
