医药导报2012，Vol.31Issue(11)：1412-1415,4.DOI:10.3870/yydb.2012.11.007
细辛止咳平喘药效物质基础初步研究
Preliminary Study on Material Basis of Asari Radix et Rhizoma Against Asthma and Cough
摘要
Abstract
Objective To explore the material basis of Asari Radix et Rhizoma for relieving asthma and cough. Methods To establish the HPLC finger prints of different extracts which were isolated with a gradient series of solvents. The relationship of cough relieving and asthma preventing with relative peak areas in the finger prints was analyzed to priliminarily determine active components. Results The extracts, HPLC finger prints of Asari Radix et Rhizoma and correlation coefficient of 41 chromatographic peaks were obtained. Conclusion The constituents corresponded to 12 chromatographic peaks are active basis of Asari Radix et Rhizoma, in which X21 is Methyl eugenol and 11 activity constituents are detected in HPLC finger prints of Asari Radix et Rhizoma gel.关键词
细辛/细辛凝胶/物质基础/色谱法,高效液相Key words
Asari Radix et Rhizoma/ Asari Radix et Rhizoma gel/ Material basis/ HPLC分类
医药卫生引用本文复制引用
刘晶,孟莉,袁子民,张会宗..细辛止咳平喘药效物质基础初步研究[J].医药导报,2012,31(11):1412-1415,4.基金项目
辽宁省科学技术厅科技计划项目(2009225010-33) （2009225010-33）
辽宁省教育厅高校科研计划项目(2009A486) （2009A486）
辽宁科学事业公益研究基金项目计划[辽科发(2011)49号] （2011）
