摘要
Abstract
Objective To investigate the relationship between relevant factors in the formation of carotid atherosclerotic plaque and severity of arterial lesion in patients with carotid atherosclerosis. Methods From October 2010 to December 2011 in our hospital, 180 patients which underwent carotid color Doppler ultrasound were selected and divided into plaque group (86 cases) and non-plaque group(94 cases). The clinical data of patients were recorded,and the indexes of venous blood lipid were determined. The relationship between blood lipid indexes and plaque formation was analyzed with logistic regression. Results The results of one-factor analysis of variance demonstrated that the relevant factors such as hypertension, diabetes , history of alcohol consumption, and TC, TG, HDL-C, ApoA, Lp (a), FIB of lipid biochemical test in plaque group were significantly higher than those in non-plaque group (P < 0. 05). Meanwhile, the age, gender, smoking history, LDL-C and ApoB had no significant difference between two groups ( P > 0. 05 ) . The results of multifactor analysis of variance demonstrated that hypertension, diabetes, Lp( a) ,TC,TG were positively correlated with the incidence of carotid atherosclerosis. Con-Ctusion The formation of carotid atherosclerotic plaque is a multi-factor-involved process, and hypertension, diabetes, Lp (a) ,TC,TG are risk factors,but HDL-C is a protective factor.关键词
颈动脉粥样硬化/心脑血管疾病/危险因素/斑块形成Key words
Carotid atherosclerosis/Cardiovascular and cerebrovascular diseases/Risk factor/Formation of Plaque分类
医药卫生
