原子能科学技术2012，Vol.46Issue(z1)：84-88,5.
18F-FDG放射化学纯度分析方法的建立及方法不确定度的评定
Establishment and Uncertainty Evaluation of Analytical Method for Radiochemical Purity of 18F-FDG
柳银黎 1王晓静 1尹光荣 1赵秀岩 1叶肇云1
作者信息
- 1. 原子高科股份有限公司,北京 102413
- 折叠
摘要
Abstract
The analytical method of I8F-FDG radiochemical purity was established. The mixed solution of acetone-water (50 ! 20 (V/V)) was used as developing reagent. Whatman No. 1 paper pre-processed with 2% KA1SO4 solution was used as stationary phase. The Ri values of 18F~ and 18F-FDG are 0 and 0. 78, respectively. The relative standard deviation is less than 1%. This method is simple, rapid, and suitable for radiochemical purity analysis of 18F-FDG injection. The uncertainty of analysis method for the radiochemical purity was evaluated. The expanded uncertainty u of this method is 0. 199 1, and u is derived from the synthesis uncertainty (mc = 0. 095 00) and the coverage factor (k = 2. 096).关键词
18F-FDG/放射化学纯度/分析方法/不确定度Key words
lsF-FDG/ radiochemical purity/ analytical method/ uncertainty分类
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柳银黎,王晓静,尹光荣,赵秀岩,叶肇云..18F-FDG放射化学纯度分析方法的建立及方法不确定度的评定[J].原子能科学技术,2012,46(z1):84-88,5.
