中国感染控制杂志2012，Vol.11Issue(5)：363-365,3.
社区获得性和医院获得性金黄色葡萄球菌感染比较
A comparative study on community- and healthcare-associated Staphylococcus aureus infection
摘要
Abstract
Objective To investigate the epidemiology and drug resistance of Staphylococcus aureus (S. aureus) from hospital and community, so as to provide reference for clinical diagnosis and treatment. Methods The isolation, identification and antimicrobial susceptibility testing of S, aureus from inpatients and outpatients from January 2008 to January 2010 were performed, epidemiological data of infected patients were studied. Results A total of 140 community-associated(CA) and 135 healthcare-associated(HA) S, aureus isolates were collected, isolation rate of methicillin-resistant Staphylococcus aureus (MRSA) in two groups was 22. 86% (32/140)and 50. 37%(68/135) respectively, the difference was significantly different (X2=22. 482,P= 0. 000) ; the main isolation sites of two groups were skin and soft tissue and respiratory tract, but constituent ratio was significantly different (X2= 79. 741,P = 0. 000) , CA-S. aureus had more sources of isolation sites. HA-S. aureus had higher resistant rate to ampicillin, ce-foxitin, tetracycline, gentamicin, chloramphenicol, rifampicin, ciprofloxacin,and imipenem than that of CA-S. aureus (all P<0. 01). Conclusion CA-S. aureus varied from HA-S. aureus in infection sites and antimicrobial resistance, pathogenic detection and antimicrobial susceptibility testing should be performed timely, antimicrobial agents should be chosen rationally, and disinfection and isolation should be paid more attention, so as to avoid the transmission of S. aureus in family and hospital.关键词
金黄色葡萄球菌/耐甲氧西林金黄色葡萄球菌/社区获得性/医院获得性/医院感染/抗药性/微生物Key words
Staphylococcus aureus / methicillin-resistant Staphylococcus aureus / community-associated infection/ healthcare-associated infection/ drug resistance, microbial分类
医药卫生引用本文复制引用
张明霞,许铮,周惠琴,余勇,吴永友..社区获得性和医院获得性金黄色葡萄球菌感染比较[J].中国感染控制杂志,2012,11(5):363-365,3.基金项目
苏州市科技发展计划指导项目(SZD09104) （SZD09104）
