中国康复2012，Vol.27Issue(4)：271-273,3.DOI:10.3870/zgkf.2012.04.011
老年PD患者血尿酸水平与抑郁、认知障碍的关系
The relationship of serum uric acid level with depression and cognitive dysfunction in elderly patients with PD
尤志珺 1刘丹荣1
作者信息
- 1. 湖北医药学院附属人民医院老年病三区,湖北十堰,442000
- 折叠
摘要
Abstract
Objective: To investigate the change of serum uric acid level and its relationship with depression and cognitive dysfunction in old patients with Parkinson disease( PD). Methods: Serum uric acid was measured in 55 elderly PD patients (PD group)and 55 healthy elderly people (control group). Elderly PD patients were measured by Hamilton depression rating scale( HAMD) and Mini-mental stale examination scale( MMSE). Results:The level of serum uric acid of PD group was significantly lower than that of control group(P<0. 05) ,and the level of serum uric acid of PD patients with depression or cognitive dysfunction was significantly lower than that in PD patients without depression or cognitive dysfunction (all P<0. 05). The MMSE score in PD group with depression was significantly lower than that in PD patients without depression(P<0. 05). Conclusions:The level of serum uric acid in elderly PD patients is decreased significantly,which even lower in elderly PD patients with depression or cognitive dysfunction.关键词
老年帕金森病/尿酸/抑郁/认知Key words
elderly Parkinson disease/ uric acid/ depression/ cognitive分类
医药卫生引用本文复制引用
尤志珺,刘丹荣..老年PD患者血尿酸水平与抑郁、认知障碍的关系[J].中国康复,2012,27(4):271-273,3.
