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安非他酮与帕罗西汀治疗抑郁症的治疗依从性对照研究

严伟良

中国临床药理学杂志2012,Vol.28Issue(10):731-733,3.
中国临床药理学杂志2012,Vol.28Issue(10):731-733,3.

安非他酮与帕罗西汀治疗抑郁症的治疗依从性对照研究

A control study of bupropion and paroxetine in the treatment compliance of patients with depression

严伟良1

作者信息

  • 1. 浙江省绍兴市第七人民医院心身疾病科,浙江绍兴312000
  • 折叠

摘要

Abstract

Objective To investigate the efficacy of bupropion and paroxetine in the treatment of patients with depression. Methods Sixty patients met CCMD - 3 depression diagnostic criteria were randomly divided into 2 groups treated with bupropion and paroxetine respectively. The efficacy and adverse reactions were evaluated at week 1st, 2th, 4th and 6 th after the drug administration. Results The onset times of depressive symptoms improvement in two groups were similar. The decline of HAMD scores was not statistically significant between two groups at the end of 6 weeks. But the adverse reactions of bupropion were less than those of paroxetine. Conclusion Bupropion can improve the treatment compliance of depressive patients.

关键词

安非他酮/帕罗西汀/抑郁症

Key words

bupropion/ paroxetine/ depression

分类

医药卫生

引用本文复制引用

严伟良..安非他酮与帕罗西汀治疗抑郁症的治疗依从性对照研究[J].中国临床药理学杂志,2012,28(10):731-733,3.

中国临床药理学杂志

OA北大核心CSCDCSTPCD

1001-6821

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