中国临床药理学杂志2012，Vol.28Issue(10)：752-754,3.
2008至2010年3年细菌的耐药监测研究
Surveillance of antimicrobial resistance in clinical isolates in our hospital from 2008 to 2010
毛静 1贾蓓 1黄文祥 1李崇智 1刘成伟1
作者信息
- 1. 重庆医科大学附属第一医院 感染科,重庆400016
- 折叠
摘要
Abstract
Objective To analyze the tendency and antimicrobial resistance of clinical isolates in our hospital from 2008 to 2010. Methods Disk diffusion method was used to determine the antimicrobial susceptibility. And the WHONET 5. 4 software was used to analyze the data based on the annual CLSI. Results Of 4916 clinical isolates, gram -positive organisms accounted for 22. 7% , and gram - negative organisms 77. 3%. The detection rates of methicillin — resistant Staphylococcus au-reus ( MRSA ) and coagulase — negative staphylococci ( MRCNS ) were 59. 3% and 89. 5% .respectively. Total extended - spectrum β lactamas-es ( ESBLs) - producing Escherichia coli and Klebsiella spp were accounted for 57. 5% and 34.6% , respectively. The carbapenem resistance rate in Acinetobacter Spp has increased year by year. There was a decreased tendency for the carbapenem resistance rate in Pseudomonas aeruginosa. Conclusion Gram - positive bacteria are still susceptible to the vancomycin teicoplanin and linezolid. Enterbacteriaceae bacteria are still very sensitive to carbapenems. But, the ESBLs - producing strains in Enterobacteriaceae are more resistant than none strains. Acinetobacter baumannii are more drug resistant, comparing to Pseudomonas aeruginosa.关键词
细菌/抗菌药物/耐药性监测Key words
bacteria/ antibacterial agents /antimicrobial resistance分类
医药卫生引用本文复制引用
毛静,贾蓓,黄文祥,李崇智,刘成伟..2008至2010年3年细菌的耐药监测研究[J].中国临床药理学杂志,2012,28(10):752-754,3.
