中国临床医学2012，Vol.19Issue(4)：345-346,2.
活性氧物质和超氧化物歧化酶与稽留流产的关系
Reactive Oxygen Species and Superoxide Dismutase Were Correlated with Missed Abortion
摘要
Abstract
Objective:To study whether reactive oxygen species(ROS) and superoxide dismutase(SOD) in placental villous tissue were related with missed abortion. Methods: Twenty patients with missed abortion (study group) and twenty early pregnant women undergoing abortion surgery (control group) were enrolled in this study. In patients with missed abortion the time embryos stayed in uterus after they died was less than four weeks. Fluorescent staining method and chemiluminometry were used to detect the levels of ROS and SOD in placental villous tissue. Results: The level of ROS in the study group was significantly higher than that in the control group ( P＜ 0. 05) , while the level of SOD in the study group was significantly lower than that in the control group ( P＜ 0. 05). Conclusions: The imbalance of ROS and SOD in placental villous tissue may be an important cause of missed abortion.关键词
活性氧物质/超氧化物歧化酶/稽留流产/流式细胞仪/化学发光分析法/绒毛Key words
Reactive oxygen species/ Superoxide dismutase/ Missed abortion/ Flow cytometry/ Chemiluminometry/Villi分类
医药卫生引用本文复制引用
朱丽均,陈亚萍,陈炳锦,梅小会..活性氧物质和超氧化物歧化酶与稽留流产的关系[J].中国临床医学,2012,19(4):345-346,2.基金项目
上海市闵行区自然科学研究课题资助项目(编号:2009MHZ088) （编号:2009MHZ088）
