中国临床医学影像杂志2012，Vol.23Issue(9)：613-616,4.
18F-FDG PET显像与EEG在颞叶癫痫致痫灶定位价值上的对比研究
Comparative studies of the value of 18F-FDG PET and EEG in temporal epilepsy patients
摘要
Abstract
Objective: To prospectively evaluate the efficacy of 18F-FDG PET/CT brain imaging and electroencephalogram (EEG) in preoperative localization of temporal lobe epileptic focus in 62 patients. Methods: Sixty—two patients who were clinically diagnosed as temporal lobe epilepsy and received surgical treatment were prospectively studied. All of those patients underwent interictal PET-CT brain imaging examination and long-range/video EEG examination prior to surgery. The researchers analyzed all the images and test results obtained and compared with postoperative pathology. The diagnostic accuracy between the two methods were compared and analyzed using statistical methods. Results: The rate of accuracy in locating epileptic focus was 67.7%(42/62) for PET/CT brain imaging and 48.4%(30/62) for long-range or video EEG, there was significant difference of accurate localization rate between the two methods (P＜0.05). Conclusion: Interictal PET-CT brain imaging is better than long-distance/video EEG examination in preoperative localization of temporal lobe epileptic focus. PET-CT brain imaging is too expensive, so EEG can be used as the preferred method in the clinical application. PET imaging can significantly improve the rate of accuracy in locating epileptic focus when there are difficulties in the localization of temporal lobe epileptic focus with EEG.关键词
癫痫,颞叶/正电子发射断层显像术/脑电描记术Key words
Epilepsy, temporal lobe/ Positron-emission tomography/ Electroencephalography分类
医药卫生引用本文复制引用
赵春雷,陈自谦,刘耀,钱根年,杨忠东,王楷堂,李铭山..18F-FDG PET显像与EEG在颞叶癫痫致痫灶定位价值上的对比研究[J].中国临床医学影像杂志,2012,23(9):613-616,4.基金项目
南京军区医学科技创新课题(08MA108) （08MA108）
南京军区重大课题(09Z029) （09Z029）
福建省科学发展计划重点项目(2009Y0037) （2009Y0037）
福建省自然科学基金资助项目(2009J01187). （2009J01187）
