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5-氨基酮戊酸光动力疗法治疗中重度痤疮疗效观察

陈向齐 牛高祥 刘向农 陈进木 吴洁 陈胜平

中国美容医学2012,Vol.21Issue(11):1551-1553,3.
中国美容医学2012,Vol.21Issue(11):1551-1553,3.

5-氨基酮戊酸光动力疗法治疗中重度痤疮疗效观察

Efficacy of photodynamic therapy with 5-aminolevulinicacid in the treatment of moderate to severe acne

陈向齐 1牛高祥 1刘向农 1陈进木 1吴洁 1陈胜平1

作者信息

  • 1. 福建医科大学福总临床医学院/南京军区福州总医院皮肤科 福建福州350025
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摘要

Abstract

Objective To investigate the efficacy and safety of 5-aminolevulinicacid photodynamic therapy in treatment of moderate to severe acne. Methods Fifty patients with moderate to severe acne were equally randomized into two groups, and one group was treated with 5% 5ALA-PDT with an interval of 1 week for 3 sessions while the other was only irradiated with red light once a week for 3 sessions. The patients were evaluated for efficacy after 2, 4 and 6 weeks. Adverse effects were also recorded at each visit. Results 24 cases of treatment group completed treatment.The efficacy rate of 5-aminolevulinicacid photodynamic therapy during 4, 6 weeks were 75.0% (18 cases),83.3% (20 cases) respectably, which were higher than control group. Conclusions Topical 5 -ALA -PDT has a significant effect in treatment of moderate to severe acne with few side reactions and it is more effective than the control group.

关键词

痤疮/5-氨基酮戊酸/光动力疗法

Key words

Acne/ 5-aminolevulinic acid/ Photodynamic therapy

分类

医药卫生

引用本文复制引用

陈向齐,牛高祥,刘向农,陈进木,吴洁,陈胜平..5-氨基酮戊酸光动力疗法治疗中重度痤疮疗效观察[J].中国美容医学,2012,21(11):1551-1553,3.

中国美容医学

1008-6455

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