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抑癌基因CpG岛甲基化与结直肠癌关系的研究进展

彭星宇

中国普通外科杂志2012,Vol.21Issue(10):1279-1282,4.
中国普通外科杂志2012,Vol.21Issue(10):1279-1282,4.

抑癌基因CpG岛甲基化与结直肠癌关系的研究进展

CpG island methylation of tumor suppressor genes in colorectal cancer

彭星宇1

作者信息

  • 1. 江西省人民医院普通外科,江西南昌330006
  • 折叠

摘要

Abstract

CpG island methylation can lead to epigenetic transcription inactivation of the tumor suppressor gene, and in some circumstances it maybe the only mechanism of tumor suppressor gene inactivation, which directly results in the occurrence of the tumors. This paper overviews the relations of the CpG island methylation of the tumor suppressor gene such as Syk; and of pi5 with colorectal cancer, and also presents related problems and future considerations.

关键词

结直肠肿瘤/抑癌基因/CpG岛/甲基化/综述文献

Key words

Colorectal Neoplasms/ Tumor Suppressor Gene/ CpG Islands/ Methylation/ Review

分类

医药卫生

引用本文复制引用

彭星宇..抑癌基因CpG岛甲基化与结直肠癌关系的研究进展[J].中国普通外科杂志,2012,21(10):1279-1282,4.

基金项目

江西省科技厅资助项目(2010BSA14200). (2010BSA14200)

中国普通外科杂志

OA北大核心CSCDCSTPCD

1005-6947

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