摘要
Abstract
Objective To investigate the effect of high volume hemofiltration ( HVHF ) on inflammatory factor and hemorheology in septic patients. Methods 32 severe sepsis patients admitted to our hospital from June 2009 to October 2011 were randomly divided into treatment group and control group with each group 16 cases. The two groups were both given routine treatment. Besides, the treatment group was also given HVHF treatment 12 to 18 hours each day. IL - 6, IL - 8, IL - 10, tumor necrosis factor - α ( TNF - α ), C - reactive protein ( CRP ), heart rate ( HR ), mean arterial pressure ( MAP ) and blood oxygen saturation ( SO2 ) of the two groups were observed before and after treatment. Results The IL - 6, IL - 8, IL - 10, TNF - α and CRP after treatment between the two groups showed statistically significant differences ( P < 0. 05 ) . The heart rate, MAP and SO2 after treatment between the two groups showed statistically significant differences ( P < 0. 05 ) . Conclusion HVHF can eliminate inflammatory mediators and stabilize hemodynamics, thus improving the clinical effect for patients with sepsis.关键词
高容量血液滤过/脓毒症/血流动力学Key words
High volume hemofiltration/ Sepsis/ Hemodynamics分类
医药卫生
