中国人兽共患病学报2012，Vol.28Issue(10)：1032-1035,4.DOI:10.3969/cjz.j.issn.1002-2694.2012.10.015
类鼻疽杆菌基因组学概述及进展
Genomic overview and progression of Burkholderia pseudomallei
摘要
Abstract
Burkholderia pseudomallei is an opportunistic pathogen which can cause melioidosis, a typical tropical dis ease, referring to almost all organs. Burkholderia pseudomallei is found in widespread water and soil and can survive as long as decades, also classified as B category pathogen by the CDC of USA. With the diffusion of pathogen and the increasing nuni ber of victims, it is believed that melioidosis is unfolding. In China, Hainan and Guangdong is disaster area of melioidosis. However, study on melioidosis still could not receive enough attention with no international standard for bacteria or whole ge nome sequencing data. In view of the specificity of the pathogen, draconic prevalence of melioidosis and research barrier, it has significant benefit for public health and military use to further the research of Burkholderia pseudomallei in China. This review will point out the necessity of whole genome sequencing of Chinese standard bacteria with consideration on the data of K96243 sequencing and the development of DNA sequencing nowadays.关键词
类鼻疽伯克霍尔德杆菌/鼻疽伯克霍尔德杆菌/基因组测序/二元基因组/基因岛Key words
Burkholderia pseudomallei/ Burkholderia mallei/ genomic sequencing/ bi genome/gene island(GI)分类
生物科学引用本文复制引用
方瑶,顾江,李倩,于波,王海光,毛旭虎..类鼻疽杆菌基因组学概述及进展[J].中国人兽共患病学报,2012,28(10):1032-1035,4.基金项目
国家重大科技专项(2008ZXJ09014-007) （2008ZXJ09014-007）
