中国人兽共患病学报2012，Vol.28Issue(11)：1093-1097,5.DOI:10.3969/cjz.j.issn.1002-2694.2012.11.007
我国G2型人蛔虫和猪蛔虫的遗传多样性
Genetic diversity of Ascaris with the shared genotype G2 from humans and pigs in China
摘要
Abstract
To further discriminate; Ascaris from humans and pigs with the shared genotype G2 , 20 antosomal microsatel-lite markers together with capillary electrophoresis and the software; CERVUS V 2 .0, ARLEQUIN V3 .11 , FSTAT V2 .9 .3 and GENETIX V4 .05 wore used to analyze the genetic diversity of 69 Ascaris worms . Residts showeel that a total of 378 differ-ent alleles were eleteeteel in Ascaris from humans and 229 from pigs . There were; 14 sites out of the 20 geneie loci having the same advantage alleles in Ascaris from both hosts , hut special alleles of 18 sites for each host eleriveel from Ascaris . The average expected heterozygosities were 0 .802 and 0 .777 , and the polymorphism information content was 0 .779 and 0 .737 , respectively for Ascaris from humans and pigs . The analysis of molecular variation (AMOV A) showed 2 .6% genetic variation between populations and 68 .6% within individuals . The Fst estimates and gene flow (Nm) between two populations were 0 .0268 and 9 .08 respectively . High genetic diversity was found in Ascaris from both hosts . No obvious genetic differentiation between the two populations was revealed and gene flow between them was eleteeteel . However , the differences in specific alleles and the advantage alleles snggesteel an important genetic difference , which might serve partly as an explanation for their different host affiliation.关键词
人蛔虫/猪蛔虫/G2型/微卫星/遗传多样性Key words
Ascaris lumbricoides / Ascaris suum / genotype G2 / micro satellite / genetic diversity分类
医药卫生引用本文复制引用
周春花,彭卫东..我国G2型人蛔虫和猪蛔虫的遗传多样性[J].中国人兽共患病学报,2012,28(11):1093-1097,5.基金项目
国家自然科学基金面上项目(30972580/C150702)资助 （30972580/C150702）
