中国人兽共患病学报2012，Vol.28Issue(11)：1130-1132,1154,4.DOI:10.3969/cjz.j.issn.1002-2694.2012.11.015
动物源产气荚膜梭菌耐药性的研究进展
Research progress on antimicrobial resistance in Clostridium perfringens of animal origin
摘要
Abstract
Clostridium perfringens is an important zoonotic pathogen that can cause; various diseases in animals and hu -mans . The antimicrobial resistance in Clostridium perfringens is common in animal production . M ost of the resistant genes in Clostridium perfringens locate on the conjngative plasm ids or mobile genetic elements , which accelerate its dissemination . In this article , the resistance mechanism of Clostridium perfringens to the commonly used antimicrobials including tetracyclines , macrolides , lincosamides , streptogramins , cloramphenicol and bacitracin was summarized . In addition , the role the conjngative plasmids or the mobilized transposons played in the horizontal dissemination of the resistant genes in Clostridium perfringens was clarified . The deep understanding on the resistance mechanism of Clostridium perfringens of animal origin can aid the control of this pathogen , which provides the guarantee for the food safety and human health .关键词
产气荚膜梭菌/耐药/水平扩散Key words
Clostridium perfringens / resistance/ horizontal dissemination分类
医药卫生引用本文复制引用
董卫超,刘凌,杜向党..动物源产气荚膜梭菌耐药性的研究进展[J].中国人兽共患病学报,2012,28(11):1130-1132,1154,4.基金项目
国家自然基金项目(No.31172367)资助 （No.31172367）
