中国神经再生研究（英文版）2012，Vol.7Issue(32)：2548-2553,6.DOI:10.3969/j.issn.1673-5374.2012.32.010
Constraint-induced movement therapy promotes brain functional reorganization in stroke patients with hemiplegia
Constraint-induced movement therapy promotes brain functional reorganization in stroke patients with hemiplegia
Wenqing Wang 1Aihui Wang 2Limin Yu 3Xuesong Han 4Guiyun Jiang 1Changshui Weng 5Hongwei Zhang 1Zhiqiang Zhou1
作者信息
- 1. Department of Rehabilitation Medicine,Affiliated Hospital of Chengde Medical College,Chengde 067000,Hebei Province,China
- 2. Department of Computer Tomography,Affiliated Hospital of Chengde Medical College,Chengde 067000,Hebei Province,China
- 3. Department of Anatomy,Chengde Nursing Vocational College,Chengde 067000,Hebei Province,China
- 4. Department of Computer & Information Engineering,Chengde Petroleum College,Chengde 067000,Hebei Province,China
- 5. Department of Rehabilitation Medicine,General Hospital of Chinese PLA,Beijing 100853,China
- 折叠
摘要
Abstract
Stroke patients with hemiplegia exhibit flexor spasms in the upper limb and extensor spasms in the lower limb, and their movement patterns vary greatly. Constraint-induced movement therapy is an upper limb rehabilitation technique used in stroke patients with hemiplegia; however, studies of lower extremity rehabilitation are scarce. In this study, stroke patients with lower limb hemiplegia underwent conventional Bobath therapy for 4 weeks as baseline treatment, followed by constraint-induced movement therapy for an additional 4 weeks. The 10-m maximum walking speed and Berg balance scale scores significantly improved following treatment, and lower extremity motor function also improved. The results of functional MRI showed that constraint-induced movement therapy alleviates the reduction in cerebral functional activation in patients, which indicates activation of functional brain regions and a significant increase in cerebral blood perfusion. These results demonstrate that constraint-induced movement therapy promotes brain functional reorganization in stroke patients with lower limb hemiplegia.关键词
stroke/constraint-induced movement therapy/functional MRI/lower extremity/maximum walking speed/Berg balance scale/central nervous injury/neuroimaging/regeneration/neural regenerationKey words
stroke/constraint-induced movement therapy/functional MRI/lower extremity/maximum walking speed/Berg balance scale/central nervous injury/neuroimaging/regeneration/neural regeneration引用本文复制引用
Wenqing Wang,Aihui Wang,Limin Yu,Xuesong Han,Guiyun Jiang,Changshui Weng,Hongwei Zhang,Zhiqiang Zhou..Constraint-induced movement therapy promotes brain functional reorganization in stroke patients with hemiplegia[J].中国神经再生研究（英文版）,2012,7(32):2548-2553,6.
