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急性呼吸道感染患儿540例病毒病原学特点分析

刘春艳 张辉 谢正德 赵成松

中国实用儿科杂志2012,Vol.27Issue(8):619-621,3.
中国实用儿科杂志2012,Vol.27Issue(8):619-621,3.

急性呼吸道感染患儿540例病毒病原学特点分析

Study of viral etiology of acute respiratory tract infection among pediatric outpatients in Beijing

刘春艳 1张辉 1谢正德 1赵成松1

作者信息

  • 1. 首都医科大学附属北京儿童医院北京市儿科研究所,儿科学国家重点学科,省部共建儿科重大疾病研究重点实验室,北京100045
  • 折叠

摘要

Abstract

Objective To investigate the viral pathogens among pediatric outpatients with acute respiratory tract infection in Beijing area. Methods From March 2010 to February 2011, 540 pediatric outpatients with acute respiratory tract infection were involved in our study. One throat swab specimen was collected from each patient. Multiplex poly-merase chain reactions were performed to detect respiratory viruses, including respiratory syncytial virus (RSV) type A and B, rhinovirus (RV) , influzenza virus (IFV) type A and B, parainfluenza virus (PIV) type 1-4, adenovirus (ADV) , enterovirus (EV) , human coronavirus (HCoV) , human metapneumonia virus (MPV) and human bocavirus (HBoV). Results At least one viral pathogen was detected in 306 out of 540 patients and the overall positive rate was 56.7%. Two or more viruses were identified in 34 cases and the mixed infection rate was 6.3%. IFV (16.7%) was the most prevalent virus, followed by ADV (12.8%) , EV (7.8%) , PIV (7.2%) , RSV (5.4% ), HMPV (5.0%) , RV (4.3%) , HCoV (3.0%) and HBoV infection (0.9%). The most predominant type of IFV, PIV and RSV were IFVA, PIV3 and RSVA respectively. Conclusions Viruses play an important role in respiratory tract infection in children. IFV, ADV, EV and PIV are the most important viral pathogens in pediatric outpatients with acute respiratory tract infection in Beijing area.

关键词

急性呼吸道感染/儿童/病毒

Key words

acute respiratory tract infection/ children/ virus

分类

医药卫生

引用本文复制引用

刘春艳,张辉,谢正德,赵成松..急性呼吸道感染患儿540例病毒病原学特点分析[J].中国实用儿科杂志,2012,27(8):619-621,3.

基金项目

北京市科技计划课题(Z09050700940903) (Z09050700940903)

中国实用儿科杂志

OA北大核心CSCDCSTPCD

1005-2224

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