中国实用儿科杂志2012，Vol.27Issue(10)：774-776,3.
儿童难治性癫痫外周血多药耐药相关蛋白1表达研究
Study of MRP1 expression in peripheral blood of children with refractory epilepsy
岳璇 1刘晓鸣 2袁宝强 1李瑞2
作者信息
- 1. 徐州医学院附属医院儿科,江苏徐州221000
- 2. 徐州市儿童医院,江苏徐州221000
- 折叠
摘要
Abstract
Objective To investigate the expression of multidrug resistant-associated protein 1 in the peripheral blood of children with refracotory epilepsy. Methods The expression of MRP1 was detected by RT-PCR and Western blot in children with intractable epilepsy, epilepsy controlled by anti-epileptic drugs (AEDs) and healthy ehildren.Results The two methods showed that MRP1 expression in intractable epilepsy was higher than that in epilepsy controlled by anti-epileptic drugs (AEDs) and healthy children(P< 0.05) , and there was no difference between epilepsy controlled by anti-epileptic drugs (AEDs) and healthy children.Conclusion MRP1 overexpresses in peripheral blood of children with refractory epilepsy.关键词
难治性癫痫/多药耐药相关蛋白1/儿童/外周血Key words
refactory epilepsy/ multidrug resistant-associated protein 1/ children/ peripheral blood分类
医药卫生引用本文复制引用
岳璇,刘晓鸣,袁宝强,李瑞..儿童难治性癫痫外周血多药耐药相关蛋白1表达研究[J].中国实用儿科杂志,2012,27(10):774-776,3.
