中国实用外科杂志2012，Vol.32Issue(9)：762-766,5.
腹腔镜袖状胃切除术治疗肥胖症合并2型糖尿病19例短期疗效分析
Short-term effect of laparoscopic sleeve gastrectomy for 19 obesity patients with type 2 diabetes mellitus
卓光鑽 1印慨 1常绪生 1郭翔 1王鑫 1郑成竹1
作者信息
- 1. 第二军医大学附属长海医院微创外科,上海200433
- 折叠
摘要
Abstract
Objective To evaluate the short-term effect of laparoscopic sleeve gastrectomy(LSG) on obesity patients with type 2 diabetes mellitus(T2DM). Methods 19 obesity patients with T2DM underwent LSG surgery from department of minimally invasive surgery of Changhai hospital during July 2010 to June 2011 were included, their clinical data before and after surgery were analyzed retrospectively. Result All the performations were completed under laparoscopic. There were no conversion or operative complications. No serious post-procedure complications. During 6 months of follow-up, all the patients weight, waist circumference and body mass index(BMI) was decreased, compared with those before operation (P<0.01). The percentage of excess weight loss(EWL%) at 1 week, 1 month, 3 months and 6 months after procedure was (11.68±4.07)%, (32.33±9.12)%, (55.83 + 14.11)%, (74.55±20.39)% respectively. 6 months after procedure, 15 (78.9%)T2DM cases got complete remission, the other 4 (21.1%)cases got partial remission. The level of hemoglobin Alc(HbAlc), fasting plasma glucose(FPG), homeostasis model assessment of insulin resistance (HOMA-IR) was decreased after procedure, especially the level of HbAlc was significantly decreased (P<0.01) since 1 month after procedure, and 3 months later, the HbAlc level of 15(78.9%) patients had come back to the normal range. Especially encouraging was that the level of FPG and HOMA-IR had a significant decrease just since 1 week after procedure (P<0.01). The abnormal metabolism and obesity-related complications, such as hypertension, fatty liver, osteoarticular degeneration, obstructive sleep apnea syndrome had been symptomatically improved in some degree respectively. Conclusion LSG may result in satisfactory weight loss and clinical remission of T2DM with few
complications. A longer follow-up period is needed.关键词
腹腔镜/袖状胃切除术/肥胖症/2型糖尿病Key words
laparoscopic/sleeve gastrectomy/obesity/type 2 diabetes mellitus分类
医药卫生引用本文复制引用
卓光鑽,印慨,常绪生,郭翔,王鑫,郑成竹..腹腔镜袖状胃切除术治疗肥胖症合并2型糖尿病19例短期疗效分析[J].中国实用外科杂志,2012,32(9):762-766,5.
