中国药理学通报2012,Vol.28Issue(11):1486-1488,3.DOI:10.3969/j.issn.1001-1978.2012.11.002
NK细胞及其受体在肝纤维化中的作用
Role of NK cells and its receptors in hepatic fibrosis
摘要
Abstract
The immune system plays an important role in the development of hepatic fibrosis process. Recent studies show that NK cells and their receptors arc; actively involved in the process of inhibition of hepatie fibrosis, and NK cells have targeted deist ruction to activated hepatic stellate cells. This paper reviews the role of NK cells and its receptor in hepatic fibrosis, and NK cells are expected to become a new target in the treatment of liver fibrosis in the future intervention.关键词
免疫系统/NK细胞/NK细胞受体/肝纤维化/肝星状细胞/机制研究Key words
immune system/ NK cell/ NK cell receptors/ hepatic fibrosis/ hepatic stellate cells/ mechanism分类
医药卫生引用本文复制引用
陈利,张自力,张峰,陆茵,王爱云,陈文星,郑仕中..NK细胞及其受体在肝纤维化中的作用[J].中国药理学通报,2012,28(11):1486-1488,3.基金项目
国家自然科学基金资助项目(No 30873424,81270514) (No 30873424,81270514)
教育部博士点基金资助项目(No 20103237110010) (No 20103237110010)
江苏省自然科学基金资助项目(No BK2008456) (No BK2008456)
江苏省六大人才高峰资助项目(No 2009112) (No 2009112)
江苏高校优势学科建设工程资助项目(No ysxk-2010) (No ysxk-2010)
江苏省针灸学重点实验室开放课题(No KJA200801) (No KJA200801)
南京中医药大学中药学一级学科开放课题资助(No 2011ZYX4-008) (No 2011ZYX4-008)
十一五科技支撑计划(No 2008BA151B02) (No 2008BA151B02)