中国医学科学院学报2012，Vol.34Issue(5)：437-442,6.DOI:10.3881/j.issn.1000-503X.2012.05.001
全身磁共振弥散加权成像与生长抑素受体显像在瘤源性骨质软化症的应用比较
Comparison of Whole Body Diffusion Weighted Magnetic Resonance Imaging and Somatostatin Receptor Scintigraphy for Oncogenic Osteomalacia
李烁 1薛华丹 1姜艳 2夏维波 2景红丽 3陈黎波 3孙非 4金征宇1
作者信息
- 1. 中国医学科学院 北京协和医学院 北京协和医院 放射科,北京100730
- 2. 中国医学科学院 北京协和医学院 北京协和医院 内分泌科,北京100730
- 3. 中国医学科学院 北京协和医学院 北京协和医院 核医学科,北京100730
- 4. 通用电气医疗集团磁共振产品部,北京100172
- 折叠
摘要
Abstract
Objective To compare the accuracy of whole body diffusion weighted magnetic resonance imaging (WB-DWI) with that of somatostatin receptor scintigraphy (SRS) in the detection and localization of the lesions in patients with oncogenic osteomalacia ( 00M). Methods Totally 6 patients with clinically suspected oncogenic osteomalacia were enrolled. All of them underwent WB-DWI and SRS within 2 weeks to evaluate the possible presence of tumors that lead to osteomalacia. Surgical and pathological findings were considered as the gold standard. The sensitivity, specificity, and accuracy were calculated. Results Pathology confirmed the diagnosis of two soft tissue tumors (including 1 angiolipoma and 1 mensenchumal tumor) and one bone tumor of malignant neurofibroma. The sensitivity, specificity, and accuracy in the identification of lesions in patients with oncogenic osteomalacia were 33. 33% , 100% , 66. 67% for WB-DWI and 33. 33% ,66. 67% , 50% for SRS (P>0. 05). Conclusion For adult patients with osteomalacia, WB-DWI and SRS can provide mutually supportive data and be used for identifying potential oncogenic osteomalacia.关键词
磁共振弥散加权成像/全身成像/生长抑素受体显像/骨质软化症Key words
diffusion weighted magnetic resonance imaging/whole body imaging/somatostatin receptor scintigraphy/osteomalacia分类
医药卫生引用本文复制引用
李烁,薛华丹,姜艳,夏维波,景红丽,陈黎波,孙非,金征宇..全身磁共振弥散加权成像与生长抑素受体显像在瘤源性骨质软化症的应用比较[J].中国医学科学院学报,2012,34(5):437-442,6.
