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磁共振成像在子宫内膜癌术前评估中的临床应用

任翠 薛华丹 李烁 张洁 潘卫东 孙兆勇 房洪营 孙宏毅 金征宇

中国医学科学院学报2012,Vol.34Issue(5):455-460,6.
中国医学科学院学报2012,Vol.34Issue(5):455-460,6.DOI:10.3881/j.issn.1000-503X.2012.05.004

磁共振成像在子宫内膜癌术前评估中的临床应用

Clinical Application of Magnetic Resonance Imaging in Preoperative Evaluation of Endometrial Cancer

任翠 1薛华丹 1李烁 1张洁 1潘卫东 1孙兆勇 1房洪营 1孙宏毅 1金征宇1

作者信息

  • 1. 中国医学科学院北京协和医学院北京协和医院放射科,北京100730
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摘要

Abstract

Objective To investigate the value of magnetic resonance imaging ( MRI) in the preoperative assessment of endometrial cancer. Methods Ninety-four patients with histopathologically confirmed endometrial carcinoma were retrospectively enrolled in this study. MRI findings were compared with the pathologic findings in all cases. The depth of myometrial invasion and lymph node metastasis were evaluated by T2 weighted imaging (T2WI) combined with contrast enhancement or diffusion weighted imaging ( DWI). Results A-mong these 94 patients, 62 had no or superficial myometrial involvement and 32 cases had deep myometrial involvement. Meanwhile, 24 groups of metastatic lymph nodes and 164 groups of non-metastatic lymph nodes were detected. The accuracy, specificity, sensitivity, negative predictive value, and positive predictive value of T2WI combined with contrast enhancement in discriminating no/superficial myometrial involvement from deep myometrial involvement were 88. 3% , 90. 3% , 84. 4% , 91. 8% , and 81. 8% , whereas those of T2WI combined with DWI were 81. 9% , 87. 1% , 71. 9% , 85. 7% , and 74. 2% , respectively. The accuracy, specificity, sensitivity, negative predictive value, and positive predictive value of T2WI combined with contrast enhancement in identifying metastatic lymph nodes were 89. 4% , 96. 8% , 54. 5% , 90. 9% , and 78. 3% , whereas those of T2WI combined with DWI were 91. 5% , 95. 5% , 72. 7% , 94. 3% , and 77. 4% , respectively. Conclusions T2WI combined with contrast enhancement is superior to T2WI combined with DWI in e-valuation of the depth of myometrial invasion. However, DWI is more sensitive in identifying lymph node metastasis than T2WI combined with contrast enhancement.

关键词

子宫内膜癌/磁共振成像/弥散加权成像

Key words

endometrial cancer/magnetic resonance imaging/diffusion weighted imaging

分类

医药卫生

引用本文复制引用

任翠,薛华丹,李烁,张洁,潘卫东,孙兆勇,房洪营,孙宏毅,金征宇..磁共振成像在子宫内膜癌术前评估中的临床应用[J].中国医学科学院学报,2012,34(5):455-460,6.

中国医学科学院学报

OA北大核心CSCDCSTPCDMEDLINE

1000-503X

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