中国医学科学院学报2012，Vol.34Issue(5)：461-467,7.DOI:10.3881/j.issn.1000-503X.2012.05.005
高场磁共振在Graves眼病患者眼外肌定量测量中的应用价值
Quantitative Evaluation of Extraocular Muscle with High-field Magnetic Resonance in Patients with Graves' Ophthalmopathy with Upper-lid Retraction
陈钰 1孙宏毅 1冯逢 1金征宇 1张竹花 1徐冬冬 1孟薇 1姜波 1房洪营 1孙照勇 1陈颖1
作者信息
- 1. 中国医学科学院北京协和医学院北京协和医院放射科,北京100730
- 折叠
摘要
Abstract
Objective To evaluate the feasibility of high-field magnetic resonance in measuring the thickness and width of extraocular muscles, calculate the ratio of thickness to width, and summarize the characters of the diameters and its ratio in patients with Gaves' ophthalmopathy ( GO) with upper-lid retraction. Methods Sixteen GO patients with upper-lid retraction ( GO group) and 14 healthy control group were enrolled in this study. All the patients underwent enhanced high-field magnetic resonance orbital scan. The thickness and width of extrocular muscles were measured on axial, coronal or oblique sagittal enhanced Tl weighted images. The ratio of thickness to width ( Rl) and width to thickness ( R2 ) were calculated. The diameters or ratio was evaluated as enlarged when they were 2 standard deviation greater than mean values of extraocular muscle in healthy control. Results The thickness of levator palpebrae superioris, medial rectus, and inferior rectus muscles in GO group were significantly larger than those in the control group (P = 0. 000, P =0. 017, P -0. 032, respectively). The width of superior oblique muscles in GO group was significantly larger than that in control group (P - 0. 000). The Rl values of levator palpebrae superioris, inferior rectus, medial rectus, and lateral rectus muscles in GO group were significant larger than those in the control group (P - 0. 000, P - 0. 037, P = 0. 019, P = 0. 032, respectively). The R2 value of superior oblique muscles was significant larger than that in the control group (P -0. 027 ). Aslo in GO group, 32 extraocular muscles showed an increased thickness. 47% of thickened extraocular muscles had an increased Rl. Conclusions Enhanced orbit imaging with high-field magnetic resonance is helpful in the quantitative assessment of the thickness and width of extraocular muscles. In GO patients, in addition to the levator palpebrae superioris muscles, some other extraocular muscles also becomes thicker. Moreover, the increased diameters of superior oblique muscles is mainly due to the increase of its width. Rl and R2 values can reflect the thickness and width of extraocular muscles and their relationship.关键词
磁共振/Graves眼病/上睑退缩/眼外肌Key words
magnetic resonance/Graves' ophthalmopathy/upper-lid retraction/extraocular muscle分类
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陈钰,孙宏毅,冯逢,金征宇,张竹花,徐冬冬,孟薇,姜波,房洪营,孙照勇,陈颖..高场磁共振在Graves眼病患者眼外肌定量测量中的应用价值[J].中国医学科学院学报,2012,34(5):461-467,7.
