中国医学科学院学报2012，Vol.34Issue(5)：480-485,6.DOI:10.3881/j.issn.1000-503X.2012.05.008
CT和磁共振成像在肝细胞癌射频治疗后射频边缘评价中的作用
Comparison of Computed Tomography versus Magnetic Resonance Imaging in Assessing Radiofrequency Ablation Margins after Radiofrequency Ablation in Patients with Hepatocellular Carcinomas
摘要
Abstract
Objective To assess the diagnostic value of magnetic resonance imaging ( MRI) in the follow-up of patients with hepatocellular carcinomas treated with radiofrequency ablation ( RFA ) and to compare it with that of computed tomography (CT). Methods From December 2009 to September 2011, 40 patients (47 hepatocellular carcinomas) were treated with RFA after transcatheter arterial chemoembolization and underwent MRI and CT for follow-up. RFA margins were assessed on a five-point scale with receiver operating characteristic curve analysis. Sensitivity, specificity, positive predictive value, negative predictive value, and accuracy were evaluated. Results The interobserver agreement rate for MRI was significantly higher (Kappa = 0. 935 ) than for CT (Kappa = 0. 714; P < 0. 05 ). The scores of 1 and 5 points for MRI, which confirms the presence or absence of residual tumor, accounted for 89.4% (84/94) , while for CT accounting for only 31.9% (30/94). The area under the receiver operating characteristic curve of MRI was significantly higher than that of CT (P < 0. 05 ) , as were the sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of detection rate ( mean, 100% , 96. 4% , 76. 9% , 100% , and 96. 8% for MRI, respectively, is. 30. 0% , 57. 1% , 10. 3% , 87. 7% , and 63. 8% for CT). Conclusion MRI is superior to CT in assessing the RFA margins in terms of the diagnostic accuracy and detection rate .关键词
肝肿瘤/导管消融术/磁共振成像/CTKey words
liver neoplasms/catherter ablation/magnetic resonance imaging/CT分类
医药卫生引用本文复制引用
曲金荣,黎海亮,刘翠翠,张宏凯,李祥,张建伟,骆俊朋,邵楠楠,张首宁,李彦乐..CT和磁共振成像在肝细胞癌射频治疗后射频边缘评价中的作用[J].中国医学科学院学报,2012,34(5):480-485,6.基金项目
河南省科技厅重点科技攻关项目(102102310006)和河南省卫生科技创新型人才工程专项(201004057) （102102310006）
