首页|期刊导航|中华医学杂志（英文版）|Characteristic findings of malignant melanoma in the sinonasal cavity on magnetic resonance imaging
中华医学杂志（英文版）2012，Vol.125Issue(20)：3687-3691,5.DOI:10.3760/cma.j.issn.0366-6999.2012.20.016
Characteristic findings of malignant melanoma in the sinonasal cavity on magnetic resonance imaging
Characteristic findings of malignant melanoma in the sinonasal cavity on magnetic resonance imaging
摘要
Abstract
Background Malignant sinonasal melanoma (MSM) is a rare tumor with a perplexing signal intensity due to variable histopathologic components.This study was undertaken to delineate its MR imaging features.Methods MR imaging findings of 10 patients (6 women and 4 men,mean age 61.3 years old) with pathologically confirmed MSM were retrospectively reviewed.The location,size,signal intensity,enhancement,and internal imaging characteristics of all tumors were evaluated.Signal intensity and degree of enhancement was graded in comparison with the gray matter and adjacent muscle uptake,respectively.Results There were 8 tumors that were pathologically confirmed to contain melanin.Compared to gray matter of the brain,7 of them demonstrated hyperintensity on T1WI and 6 (6/7) showed hypointensity on T2Wl.There was multiple linear,dark-signal intensity on T2WI within the mass in 9 of the 10 patients' tumors.Evaluated with gadolinium-enhanced imaging,all 10 patients showed moderate enhancement within the areas that were isointense in the lesion on pregadolinium T1WI.Moreover,some parts which displayed hyperintensity on T1WI within the tumors of 7 patients showed mild enhancement that was similar to muscle on a time-intensity curve (TIC).Conclusions MSM shows characteristic MR signal intensity (hyperintensity on T1WI and the linear,low-signal intensity on T2WI),which may provide valuable information for clinical diagnosis.Together with conventional MRI,TIC may be useful for indicating pleomorphic patterns of MSM.关键词
malignant melanoma/nasal cavity/magnetic resonance imagingKey words
malignant melanoma/nasal cavity/magnetic resonance imaging引用本文复制引用
XU Qing-gang,FU Li-ping,WANG Zhen-chang,XIAN Jun-fang,HE Li-yan,ZHANG Zheng-yu,LIU Cheng-yao..Characteristic findings of malignant melanoma in the sinonasal cavity on magnetic resonance imaging[J].中华医学杂志（英文版）,2012,125(20):3687-3691,5.基金项目
This study was financially supported by the China Postdoctoral Science Foundation(No.20090461433),and the National Natural Science Foundation of China(No.30900352). （No.20090461433）
