中山大学学报（医学科学版）2012，Vol.33Issue(5)：664-667,4.
自身免疫性甲状腺疾病患者血清C1q抗体的变化
Serum Anti-C1q Antibodies in Patients with Autoimmune Thyroid Disease
徐明彤 1姜力丹 1黎锋 1唐菊英 1薛声能 1柴佳妮 1严励1
作者信息
- 1. 中山大学孙逸仙纪念医院内分泌科,广东广州510120
- 折叠
摘要
Abstract
[Objective] To investigate serum anti-Clq antibodies (C1q Ab) levels in the patients with autoimmune thyroid disease,and the correlation between serum levels of Clq Ab and thyroid function, thyroid auto-antibodies is analyzed. [Methods] The serum levels of C1q Ab in 28 Graves disease patients (GD group), 34 in chronic lymphocytic thyroiditis patients (CLT group) and 27 healthy subjects (CON group) were detected by enzyme-linked immunosorbent assay (ELISA). [Results] Serum levels of C1q Ab were 3.130 (2.773-3.833) U/mL in the CON group, 4.625 (2.888-11.798) U/mL in the GD group and 3.125 (2.750-4.625) U/ mL in the CLT group respectively. Patients with GD were positive more frequently for anti-C1q than controls. Absolute values of serum anti-C1q levels in the GD group were higher than that in the CON group, and correlated positively with TRAb. However, serum levels of Clq Ab in the CLT group showed a negative correlation with TT4. [Conclusions] Serum levels of C1q Ab in the GD group were higher than that in the CON group, and correlated positively with TRAb. And serum levels of C1q Ab in the CLT group correlated negatively with TT4.关键词
C1q抗体/Graves病/慢性淋巴细胞性甲状腺炎Key words
anti-C1q antibodies/ Graves' disease/ chronic lymphocytic thyroiditis分类
医药卫生引用本文复制引用
徐明彤,姜力丹,黎锋,唐菊英,薛声能,柴佳妮,严励..自身免疫性甲状腺疾病患者血清C1q抗体的变化[J].中山大学学报（医学科学版）,2012,33(5):664-667,4.
