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短时受精对体外受精妊娠结局的影响

李瑞岐 王文军 黄丽丽 马芸 欧阳能勇 麦美琪 陈静华 张宁锋 区颂邦

中山大学学报(医学科学版)2012,Vol.33Issue(5):683-686,4.
中山大学学报(医学科学版)2012,Vol.33Issue(5):683-686,4.

短时受精对体外受精妊娠结局的影响

Effect of Short Time Insemination on Outcome of In Vitro Fertilization

李瑞岐 1王文军 1黄丽丽 1马芸 1欧阳能勇 1麦美琪 1陈静华 1张宁锋 1区颂邦1

作者信息

  • 1. 中山大学孙逸仙纪念医院生殖中心,广州510120
  • 折叠

摘要

Abstract

[Objective] To assess the effect of short time insemination (2 hours, 2 h) on the polyspermy rate and the outcome of in vitro fertilization (IVF). [Methods] In this prospective study, 658 patients were randomized divided into short time insemination group (group A) and standard insemination group (group B). The rates of fertility, polyspermy, usable embryos, clinical pregnancy and implantation were studied, [outcome] Sixty-one patients of the total participates were excluded because of no embryos available. The data of the other 597 patients were analyzed. There were 294 patients in the short co-incubation group and 303 patients in the standard insemination group. The fertility rate was significantly lower in group A than that in group B (68.8% vs 72.1%, P < 0.05). But the rates of polyspermy (11.4% vs 11.7%, P>0.05), usable embryos (86.5% vs 86.1%, P>0.05), clinical pregnancy (47.6% vs 42.6%, P > 0.05) and implantation (28.6% vs 26.5%, P > 0.05) had no significant differences, [conclusion] 2 h insemination did not improve the polyspermy rate and the outcome of IVF.

关键词

短时受精/多精受精率/妊娠率/种植率

Key words

short time insemination/ polyspermy rate/ pregnancy rate/ implantation rate

分类

医药卫生

引用本文复制引用

李瑞岐,王文军,黄丽丽,马芸,欧阳能勇,麦美琪,陈静华,张宁锋,区颂邦..短时受精对体外受精妊娠结局的影响[J].中山大学学报(医学科学版),2012,33(5):683-686,4.

基金项目

国家自然科学基金(81070466) (81070466)

广东省科技计划项目(2010B031600043) (2010B031600043)

中山大学学报(医学科学版)

OA北大核心CSCDCSTPCD

1672-3554

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