中药材2012，Vol.35Issue(6)：973-977,5.
中心组合设计-响应面分析法优选莽吉柿果皮中α-mangostin的超声提取工艺
Optimize Technique of Extracting α-mangostin from Pericarp of Garcinia mangostana by Supersonic Wave Using Central Composite Design-Response Surface Methodology
摘要
Abstract
Objective: To optimize the extraction technique for α-mangostin from pericarp of Garcinia Mangostana. Methods: The effects of ethanol concentration, ultrasonic extraction time, the liquid to solid ratio and their interaction on extraction rate were studied by central composite design. The predictive model and reliability were developed by SAS software and response surface analysis. The optimal ultrasonic extraction conditions were achieved. Results; The optimal ultrasonic extraction conditions were as follows; ethanol concentration 67. 8% , ultrasonic extraction time 85. 9 min, the liquid to solid ratio 24. 2 mL/g. Under the optimum conditions, the extraction yield of α-mangostin was 5. 53%. Conclusion: This study provides an effective method for the industrial extraction of α-man-gostin.关键词
莽吉柿/α-mangostin/提取工艺/中心组合设计/响应面分析Key words
Garcinia mangostana L / α-mangostin/ Extraction technique/ Central composite design/ Response surface analysis分类
医药卫生引用本文复制引用
赵岩,唐强,金达明,王鑫,张连学..中心组合设计-响应面分析法优选莽吉柿果皮中α-mangostin的超声提取工艺[J].中药材,2012,35(6):973-977,5.基金项目
国家自然科学基金(31000154) （31000154）
国家科技支撑计划项目(2011BAI03B01) （2011BAI03B01）
吉林省教育厅"十二五"科学技术研究资助项目(2011-36) （2011-36）
吉林省科技发展计划项目(20111615) （20111615）
