摘要
Abstract
To investigate the therapeutic efficacy of Qibai Pingfei Capsules in the treatment of chronic obstructive pulmonary disease (COPD) associated with depressive disorder . Methods Fifty-eight COPD patients with depressive disorder were randomly divided into treatment group (re=29) and control group (re?9). On the basis of conventional therapy , Qibai Pingfei Capsules and flupentixol-melitracen were given to the treatment group and control group , respectively . The changes in hemorheological param-
eters , T lymphocyte subsets, and Hamilton depression scale (HAMD) score in both groups were observed . Results Compared with the control group, the treatment group showed significantly lower HAMD score , blood viscosity at high and low shear rates , and plasma viscosity , significantly higher CD4 cell percentage, and significantly lower CD8+ cell percentage (P<0.05 or P<0 .01) .Conclusion Qibai Pingfei Capsules can improve hemorheological properties , adjust T lymphocyte subsets , and decrease HAMD score in COPD patient with depressive disorder , achieving good therapeutic efficacy .关键词
特发性间质性肺炎/间质流膏/临床影像生理评分/转化生长因子β1/肿瘤坏死因子αKey words
Qibai Pingfei Capsule / chronic obstructive pulmonary disease / depressive disorder / Hamilton depression scale / hemorheological/ T lymphocyte subset分类
医药卫生
