北京大学学报（医学版）2012，Vol.44Issue(6)：937-941,5.DOI:10.3969/j.issn.1671-167X.2012.06.027
淋巴结转移阴性直肠癌患者的预后因素分析
Analysis of prognostic factors in patients with lymph node-negative rectal cancer
武颖超 1李沈 1汪欣 1刘玉村 1万远廉 1黄珊君1
作者信息
- 1. 北京大学第一医院普通外科,北京100034
- 折叠
摘要
Abstract
Objective: To investigate the risk factors for the prognosis in patients with node-negative rectal cancer. Methods; Clinicopathological characteristics of 117 patients with lymph node-negative rectal carcinoma undergoing curative rectectomy from January 2005 to December 2008 were retrospectively analyzed. Results; The overall 5-year survival rate was 91.5%. The univariate analysis revealed that tumor size (x2= 8. 422 ,P =0. 004) , invasive depth(T staging,x2=9.448 ,P =0. 024) , cell differentiation (x2= 26. 571 ,P =0.000) , pathologic type (x2 =4. 712,P =0. 030) and preoperative level of carci-noembryonic antigen (x2=4. 131, P =0.042) had significant effects on the survival. In multivariate analysis, the independent prognostic factors for these patients were tumor size ( Wald = 5. 286, P = 0. 022 ) , cell differentiation ( Wald = 7. 172, P = 0. 007) and invasive depth ( T staging, Wald = 5.741, P=0.017). Conclusion; For node-negative rectal cancer patients, tumor size, poor differentiation and invasive depth are important markers to evaluate their prognosis.关键词
直肠肿瘤/淋巴转移/病理学,临床/外科手术/预后Key words
Rectal neoplasms/ Lymphatic metastasis/ Pathology, clinical/ Surgical procedures, operative/ Prognosis
分类
医药卫生引用本文复制引用
武颖超,李沈,汪欣,刘玉村,万远廉,黄珊君..淋巴结转移阴性直肠癌患者的预后因素分析[J].北京大学学报（医学版）,2012,44(6):937-941,5.
