发光学报2012，Vol.33Issue(11)：1187-1191,5.DOI:10.3788/fgxb20123311.1187
脂溶性CdSe/ZnS量子点脂质体复合物的制备及表征
Preparation and Characterization of Liposome Coated Hydrophobic CdSe/ZnS Core-shell QDs
摘要
Abstract
In the organic phase, hydrophobic CdSe/ZnS core-shell quantum dots (QDs) were synthesized successfully using a free-phosphine and non-injecction method. The transmission electron microscopy (TEM) shows CdSe/ZnS core-shell nanocrstals with an average diameter of 4.5 nm. The fluorescence quantum yield of the QDs, calibrated with fluorescein using a 470 nm laser, was found to be 29%, which was greatly increased compared with bare CdSe QDs, indicating strong photolumines-cence. The maximum emission wavelength of QDs was 540 nm at excitation of 410 nm. Through the thin-film evaporation method, using the L-ct-phosphatidylcholine and Cholesterol, the hydrophobic CdSe/ZnS core-shell QDs were successfully embedded in the two-layer of liposome. As the amphipa-thy of phospholipid molecules, rendering the luminescent hydrophobic CdSe/ZnS core-shell QDs hydrophilia, CdSe/ZnS core-shell QDs can be transferred in water without extra surface combining reagents. The morphology of liposome was characterized by TEM using negatively stained method, the process of CdSe/ZnS core-shell QDs embedded in the phospholipid two-layer was confirmed by inverted fluorescent microscopy under the UV light. The result indicates that CdSe/ZnS core-shell QDs embedded in the phospholipid two-layer have more photostability and more resistant photobleaching.关键词
CdSe/ZnS核壳量子点/脂质体/荧光Key words
CdSe/ZnS core-shell QDs/ liposome/ fluorescence分类
数理科学引用本文复制引用
邵太丽,李萍,赵志刚,宋雪飞,朱昌青..脂溶性CdSe/ZnS量子点脂质体复合物的制备及表征[J].发光学报,2012,33(11):1187-1191,5.基金项目
省教育厅自然科学基金(KJ2011Z397) （KJ2011Z397）
校中青年科研基金(WK201020)资助项目 （WK201020）
