分析测试学报2012，Vol.31Issue(12)：1572-1576,5.DOI:10.3969/j.issn.1004-4957.2012.12.018
以三(2-氨基乙基)胺为核的PAMAM与Zn2+的络合作用研究
Research on Complexation between PAMAM Dendrimer with a Tri (2-aminoethyl) amine Core and Zn2+
摘要
Abstract
Different generatons of polyamidoamine dendrimers ( PAMAM ) with tri (2-aminoethyl) a-mine at the core were synthesized using divergent synthesis. The products were characterized by FTIR and H NMR. The results showed that the products synthesized had a precise molecular structure and the molecular structure was also correspond to the theoretical structure of the PAMAM dendrimers. The PAMAM possess a large number of primary amine groups, tertiary amine groups and amide groups, which can complex with Zn2 + . In this paper, the complexation between PAMAM dendrimers and Zn2+ were studied by fluorescence spectrophotometry, and effects of the generation of PAMAM, molar ratio of Zn2+ to PAMAM, pH value of the solution, reaction temperature and reaction time on the complexation were discussed. The results showed that the number of complexed Zn2+ increased with the increase of generation of PAMAM and the experimental results were almost simlar to the theory value. As the molar ratio of Zn2+ to PAMAM increased, the complex forms cuold chang. The pH value of the solution also had a great effect on the complexation of PAMAM - Zn2 +. The primary amine groups and tertiary amine groups of PAMAM were protonated under strong acidic conditions and Zn2 + was replaced by H + , resulting in the release of Zn2 +. This phenomenon indicated that PAMAM dendrimers could be recycled. It was also found that the reaction temperature and reaction time could influence the complexation of Zn - PAMAM dendrimers. The reaction extent of complex system was enhanced with the increase of reaction temperature and reaction time.关键词
三(2-氨基乙基)胺/PAMAM树状大分子/Zn2+/络合/荧光分光光度法Key words
tri (2-aminoethyl) amine/ PAMAM dendrimer/ Zn2+/ complexation/ fluorescence spectrophotometry分类
化学化工引用本文复制引用
林栋,赵芹,韩景田,侯桂革,郑树娜..以三(2-氨基乙基)胺为核的PAMAM与Zn2+的络合作用研究[J].分析测试学报,2012,31(12):1572-1576,5.基金项目
滨州医学院科技计划项目(BY2011KJ085) （BY2011KJ085）
