国际医药卫生导报2012,Vol.18Issue(22):3308-3310,3.DOI:10.3760/cma.j.issn.1007-1245.2012.22.031
辛伐他汀对心肌梗死后无症状心衰患者NT-proBNP及心功能的影响效果观察
Effects observe of simvastatin treatment on plasma NT-proBNP and ventricular function in patients with silent heart failure
陈伟1
作者信息
- 1. 416000 湖南省湘西自治州人民医院心内科
- 折叠
摘要
Abstract
Objective To observe the effects of simvastatin on plasma NT-proBNP and ventricular function in patients with silent heart failure.Methods 80 patients of silent heart failure were chosen and randomly divided into control group and the treatment group,with 40 cases for each group.The control group received conventional treatment,while the treatment group was treated with simvastatin based on conventional treatment,the changes of plasma NT-proBNP level and the parameters of ventricular function before and after treatment were observed.Results The plasma NT-proBNP levels were obviously lower than those before treatment and the control group(P < 0.05);the LVEDd,FS,LVEF in treatment group were more significantly improved than those in the control group and before treatment(P<0.05).Conclusions The simvastatin can decrease NT-proBNP levels and improve ventricular function of patients with silent heart failure.关键词
辛伐他汀/心肌梗死后无症状心衰/NT-proBNP/心功能Key words
Simvastatin/Silent heart failure/NT-proBNP/Ventricular function引用本文复制引用
陈伟..辛伐他汀对心肌梗死后无症状心衰患者NT-proBNP及心功能的影响效果观察[J].国际医药卫生导报,2012,18(22):3308-3310,3.