国际妇产科学杂志2012，Vol.39Issue(6)：593-596,4.
孕激素在自发性早产防治中的研究进展
Research Progress on Progestins Treatment for the Prevention of Spontaneous Preterm Birth
别亚男1
作者信息
- 1. 523000广东东莞,广东医学院附属东莞市厚街医院妇产科
- 折叠
摘要
Abstract
Preterm birth is defined as birth between 28 and 37 completed weeks of gestation in China, and classified as either indicated preterm birth or spontaneous preterm birth. Preterm birth causes the major determinant of perinatal mortality and morbidity, and the long -term results of preterm birth often lead to neural and mental developmental defects. There is experimental support from animal and in vitro studies, and also empirical evidence from large randomized placebo-controlled clinical trials, that treatment with progestins (includes natural progesterone and its analogues) may reduce the risk of preterm birth. Progesterone has a role in maintaining pregnancy, by maintaining uterine quiescence and inhibiting cervical riping. This article reviews the use of progestins in women with high-risk factors for the prevention of spontaneous preterm birth and the safety of progestins supplementation in pregnancy.关键词
早产/胎膜早破/分娩,过早/孕激素类/孕酮Key words
Premature birth/ Fetal membranes, premature rupture/ Obstetric labor, premature/ Progestins/ Progesterone引用本文复制引用
别亚男..孕激素在自发性早产防治中的研究进展[J].国际妇产科学杂志,2012,39(6):593-596,4.
