国际医学放射学杂志2012，Vol.35Issue(6)：515-518,4.DOI:10.3784/j.issn.1674-1897.2012.06.L0602
MRI对伽玛刀治疗脑转移瘤及瘤周水肿疗效的分析
MR imaging response of cerebral metastases and peritumoral edema after Gamma Knife surgery
摘要
Abstract
Objective To evaluation the treatment response of Gamma Knife surgery (GKS) for the control of cerebral metastases and peritumoral edema using standard MRI. Method 42 consecutive patients with 75 metastatic lesions were recruited in this study (28 men, 14 women; mean age 60 ±12 years). Gadolinium enhancement T,WI scans were performed on one day before and three months after GKS. Treatment response was evaluated by calculating the changes of tumor volume and edema index before and after GKS. Results Mean tumor volumes on the baseline and post treatment were 7.0 cm3 and 3.3 cm3 respectively. Mean peritumoral edema indexes were 9.9 and 4.3 respectively. Tumor growth control rate and peritumoral edema control rate were 91% and 85% respectively. Conclusion GKS is effective for both brain metastasis and peritumoral edema, and the tumor volume influences GKS efficacy. Conventional MRI provides useful information to predict treatment response of GKS for cerebral metastasis.关键词
脑转移瘤/瘤周水肿/磁共振成像/伽玛刀/水肿指数Key words
Metastatic brain tumors/ Peritumoral brain edema/ Magnetic resonance imaging/ Gamma Knife surgery/Edema index引用本文复制引用
郭琪,王琮荫,张雪宁,郑晶晶,徐德生,张宜培..MRI对伽玛刀治疗脑转移瘤及瘤周水肿疗效的分析[J].国际医学放射学杂志,2012,35(6):515-518,4.基金项目
天津市卫生局科研基金项目(2010KZ92) （2010KZ92）
