化工学报2013，Vol.64Issue(1)：233-242,10.DOI:10.3969/j.issn.0438-1157.2013.01.025
核酸适配体在生化分离及检测领域中的研究进展
Research progress of aptamer in biochemical separation and detection
摘要
Abstract
Aptamers are short single stranded DNA or RNA oligonucleotides that exhibit high affinity and specificity to their corresponding targets. Compared to other recognition molecules, aptamers are highly stable, easier to synthesize and modify, smaller in size and specific to a wide range of targets. Until now, aptamers have shown diverse applications to detection, separation and purification studies, and development of medical treatment. This paper summarizes the research progress of aptamer in biochemical separation and detection.关键词
核酸适配体/识别分子/生化分离/检测Key words
aptamers/recognition-molecules/biochemical separation/detection分类
化学化工引用本文复制引用
李晓佩,杨良嵘,黄昆,李文松,孙西同,刘会洲..核酸适配体在生化分离及检测领域中的研究进展[J].化工学报,2013,64(1):233-242,10.基金项目
国家自然科学基金项目(21106162) （21106162）
国家自然科学重点基金项目(21136009) （21136009）
国家重点基础研究发展计划项目(2009CB219904) （2009CB219904）
化学工程国家重点实验室开放基金项目(SKL-ChE-11A04). （SKL-ChE-11A04）
