湖南中医药大学学报2012，Vol.32Issue(11)：34-37,4.DOI:10.3969/j.issn.1674-070X.2012.11.009.034.04
糙叶五加根皮化学成分研究
Study on chemical constituents from root barks of Acanthopanax henryi
摘要
Abstract
Objective To study the chemical constituents of root barks of Acanthopanax henryi (A. Henryi) based on anti-inflammatory activities. Methods The compounds were isolated and obtained by column chromatography including XAD -4, silica gel, ODS and Sephadex LH -20, combined with DART -MS technology. The structures of these compounds were elucidated by means of physiochemical properties and spectroscopic analysis. Results Seven compounds were separated and identified as stigmasterol(1), β-sitosterol(2), pimaric acid(3), (+)-sesamin(4), savinin (5), syringing (6) and eleutheroside E (7) by column chromatography. In addition, taiwanin C, 10-hydroxy-2,8-decadiene-4,6-diynoic acid, 3,7,11-trimethyl-2,6,10-dodecatrienoic acid, caffeic acid together with stigmast-7-ene-3,6-diol could be existed in root barks of Acanthopanax henryi by DART-MS compared with their standard spectrums. Conclusion Compounds 3, 4, 5, 7 were obtained from the genus for the first time.关键词
糙叶五加根皮/化学成分/结构鉴定/实时直接分析质谱Key words
root barks of Acanthopanax henryi (A. Henryi)/ chemical constituents/ structure I-dentification/ DART-MS分类
医药卫生引用本文复制引用
刘恒言,金钟焕,刘向前,陆昌洙..糙叶五加根皮化学成分研究[J].湖南中医药大学学报,2012,32(11):34-37,4.基金项目
湖南省自然科学基金重点项目(11JJ2042) （11JJ2042）
湖南省研究生科研创新项目(CX2011B348) （CX2011B348）
湖南中医药大学药物分析学"十二五"校级重点学科建设项目. （）
