化学工程2012，Vol.40Issue(12)：70-74,5.DOI:10.3969/j.issn.1005-9954.2012.12.017
2,3-丁二醇分离纯化中反应精馏工艺
Reactive distillation in 2,3-butanediol separation from fermentation broth
摘要
Abstract
Acetaldehyde-cyclohexane reactive extraction system can effectively separate 2,3-butanediol from fermentation broth. The continuous hydrolyzing process of reactive-extraction liquid was studied. Cationic ion-exchange resin HZ732 was used as catalyst. The hydrolysis rate of 2,4,5-trimethyl-1,3-dioxolane (2,3-butanediol-acetaldehyde-acetal) was used as index. The operation conditions were investigated, which include reaction temperature, reaction stage number,feeding velocity,feed mole ratio of 2,4,5-trimethyl-l ,3-dioxolane to water and reflux ratio. The appropriate operation conditions obtained are as follows: reaction temperature is 90℃ , reaction stages are 20, mole ratio of 2,4,5-trimethyl-l ,3-dioxolane to water is 0. 6, and feed velocity is 0. 2 h-1. Under above conditions, more than 73% of 2,4 ,5-trimethyl-1,3-dioxolane can be hydrolyzed to form 2,3-butanediol. Finally,distillation was used to purify 2,3-butanediol and recover the unhydrolyzed 2,4,5-trimethyl-l ,3-dioxolane. The overall yield of 2,3-butanediol can be ≥93% with purity (mass fraction) of more than 96%. The continuous hydrolyzing process can improve the hydrolysis rate of 2,4,5-trimethyl -1,3-dioxolane and can be used for industrial application.关键词
2,3-丁二醇/水解精馏/阳离子交换树脂/分离纯化Key words
2,3-butanediol/hydrolysis-distillation/cationic ion-exchange resin/ fermentation broth分类
化学化工引用本文复制引用
李琰君,朱家文,吴艳阳,刘佳娴,沈亚领..2,3-丁二醇分离纯化中反应精馏工艺[J].化学工程,2012,40(12):70-74,5.基金项目
国家自然科学基金资助项目(21106039) （21106039）
