四川大学学报（医学版）2012，Vol.43Issue(6)：904-906,3.
脑缺血大鼠肺组织中MEK的表达变化
Expression Changes of MEK in Lung of Rats Subjected to Brain Ischemia
摘要
Abstract
Objective To explore the expression changes of mitogen extracellular kinase (MEK) in injured lung after brain ischemia in rats. Methods Adult SD rats were assigned randomly to sham operation group and brain ischemia lung injury (BILI) group. Rats in BILI group were subjected brain ischemia and allowed to survived 3 d. Pathalogical changes in lung were indicated by HE staining. The MEK expression was determined by RT-PCR and Western blot technique. Results After brain ischemia, the bulk of inflammatory cells invaded into lung were observed. Upregulated level of MEK mRNA and protein were found at 3 days after ischemia (P<0. 05). Conclusion The upregulated expression of MEK implied that the MEK may play some roles in lung injury after brain ischemia.关键词
大鼠/脑缺血肺损伤/丝裂原细胞外激酶Key words
Rat/Brain ischemia lung injury/MEK引用本文复制引用
王盛兰,但齐琴,荣荣,李劲涛,张云辉..脑缺血大鼠肺组织中MEK的表达变化[J].四川大学学报（医学版）,2012,43(6):904-906,3.基金项目
云南省自然科学基金(No.2010ZC206,No.2011FZ272,No.2012fb086) （No.2010ZC206,No.2011FZ272,No.2012fb086）
