实用临床医药杂志2012，Vol.16Issue(21)：39-41,3.
负压防反流技术联合白介素-2治疗恶性胸腔积液的临床研究
Clinical research of negative anti-reflux technique combined with interleukin-2 for malignant pleural effusion
摘要
Abstract
Objective To observe the therapeutic effects and safety of negative anti-reflux technique combined with interleukin-2 (IL-2) for malignant pleural effusion. Methods A total of 196 patients with malignant pleural effusion were randomized into three groups. Group A received thoracic drainage by negative anti-reflux device. When the effusion was drained completely, IL-2 was injected through thoracic cavity. Group B received thoracic drainage by central venous catheter, IL-2 was injected through thoracic cavity when there was no effusion flowing out. Group C received conventional pleural effusion, IL-2 was injected when the effusion couldn't be pumped. Results The total effectiveness rate in group A was significantly higher than that in groups B and C. The 1 -, 2-, and 3-year survival rate in group A were significantly higher than those in groups B and C. The patients were all well tolerated and there were no serious adverse reactions or complications. Conclusion Combination of negative anti-reflux technique and IL-2 in the treatment of malignant pleural effusion has high security and effectiveness rate, and it is worthy of clinical application.关键词
负压防反流技术/恶性胸腔积液/白介素-2Key words
negative anti-reflux technique/malignant pleural effusion/interleukin-2分类
医药卫生引用本文复制引用
马长武,季洪波,尹胜杰,商迪,项庆增,王磊,王乐乐..负压防反流技术联合白介素-2治疗恶性胸腔积液的临床研究[J].实用临床医药杂志,2012,16(21):39-41,3.基金项目
中高校医学期刊临床专项资金(11220212) （11220212）
