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SOX方案在进展期胃癌患者中的临床疗效观察

宋红蕾 毕延智 徐珍 董益忠 张亚平 盛桂凤 胡岳棣

实用临床医药杂志2012,Vol.16Issue(23):20-22,3.
实用临床医药杂志2012,Vol.16Issue(23):20-22,3.

SOX方案在进展期胃癌患者中的临床疗效观察

Effect observation of SOX regimen on patients with advanced gastric cancer

宋红蕾 1毕延智 1徐珍 1董益忠 1张亚平 1盛桂凤 1胡岳棣1

作者信息

  • 1. 苏州大学附属常州肿瘤医院肿瘤内科 江苏常州 213001
  • 折叠

摘要

Abstract

Objective To explore the clinical curative effect and safety evaluation of SOX regimen on patients with advanced gastric cancer. Methods 46 patients with advanced gastric cancer were randomly divided into SOX group and control group, 23 cases in each group. SOX group was given SOX regimen, and the control group was given EOF regimen. Curative effect and adverse reactions were observed in 2 groups; KPS score was made after treatment. Results Efficiency, clinical benefit rate and adverse reaction rate between 2 groups had no significant difference (P>0. 05). The KPS score of the SOX group after treatment was (86. 4 ± 7. 9) points, the improvement rate was 68. 2% . The KPS score of the control group after treatment was (79. 4 ± 7. 5) points, the improvement rate was 34. 8% . There were statistical differences in the KPS score and improvement rate beween 2 groups (P<0. 01). Conclusion SOX regimen has a higher clinical benefit rate, mild adverse reactions, well toleration in treating patients with advanced gastric cancer, and it is worthy of application and further clinical observation.

关键词

SOX方案/进展期胃癌/临床疗效/毒副反应

Key words

SOX regimen/advanced gastric cancer/clinical curative effect/adverse reaction

分类

医药卫生

引用本文复制引用

宋红蕾,毕延智,徐珍,董益忠,张亚平,盛桂凤,胡岳棣..SOX方案在进展期胃癌患者中的临床疗效观察[J].实用临床医药杂志,2012,16(23):20-22,3.

基金项目

中国高校医学期刊临床专项资金(11220247) (11220247)

实用临床医药杂志

OACSTPCD

1672-2353

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