昆明医科大学学报2012,Vol.33Issue(11):38-41,52,5.
凉血活血中药含药血清对人脐静脉内皮细胞增殖的影响
The Effect of Medicated Serum with Liangxuehuoxue Traditional Chinese Medicines on the Proliferation of Human Umbilical Vein Endothelial Cells
摘要
Abstract
Objective To study the therapeutic effect liangxuehuoxue traditional Chinese medicines on the supression of ECV304 by serum pharmacological method, and to explore the interventional target for treatment of neovessels related eye diseases. Methods ECV304cells were cultured with medicated serum with different concentrations of liangxuehuoxue medicines. The proliferation rate of endothelial cells was assayed with MTT methods, the level of VEGF was tested. Result Medicated serum with liangxuehuoxue medicines at concentration of 20% could inhibit the proliferation of ECV304 cells and the expression of VEGF. Conclusion Liangxuehuoxue traditional Chinese medicines cna inhibit the ECV304 cells proliferation and the expression of VEGF, and this may be related to inhibition of neo vessels.关键词
凉血活血/ECV304/新生血管/VEGFKey words
Liangxuehuoxue/ ECV304/ Neovessels/ VEGF分类
医药卫生引用本文复制引用
马珊,马俊,彭华,王明芳,代自超..凉血活血中药含药血清对人脐静脉内皮细胞增殖的影响[J].昆明医科大学学报,2012,33(11):38-41,52,5.基金项目
云南省科技厅自然科学研究基金资助项目(2011FZ257) (2011FZ257)